University of Illinois Urbana-Champaign

Ultrasonic viscoelasticity imaging of nonpalpable breast lesions

Qiu, Yupeng

Content Files
Qiu_Yupeng.pdf

Permalink

https://hdl.handle.net/2142/14634

Description

Title
Ultrasonic viscoelasticity imaging of nonpalpable breast lesions
Author(s)
Qiu, Yupeng
Issue Date
2010-01-06T16:20:11Z
Director of Research (if dissertation) or Advisor (if thesis)
Insana, Michael F.
Doctoral Committee Chair(s)
Insana, Michael F.
Department of Study
Bioengineering
Discipline
Bioengineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
M.S.
Degree Level
Thesis
Date of Ingest
2010-01-06T16:20:11Z
Keyword(s)
  • Breast cancer
  • elasticity
  • diagnosis
Abstract
The prognosis of breast cancer patients improves with early and accurate diagnosis. The quality of the strain image produced by displacement estimation algorithms are heavily influenced by the RF echo data recorded by different ultrasound systems. A small clinical study was conducted with 21 women having a single nonpalpable breast lesion, each detected mammographically with later pathology confirmation. Elasticity images were acquired on each patient to test for the ability to differentiating malignant and benign lesions. The mechanical relaxation time T1 images showed a tissue-specific T1 contrast that is negative for all 11 malignant lesions and positive for all 10 benign lesions. Strain images were estimated using a regularized multi-scale optical flow (ROF) algorithm. Adjustments to the input parameters to the ROF and their subsequent effects on T1 estimation and computation time are shown to have a strong effect on diagnostic performance.
Graduation Semester
2009-12
Permalink
http://hdl.handle.net/2142/14634
Copyright and License Information
"Copyright 2009 Yupeng Qiu, portions of ""Patient Imaging"" chapter copyright 2008 by Academic Radiology."

Owning Collections

Dissertations and Theses - Bioengineering
Graduate Dissertations and Theses at Illinois PRIMARY
Graduate Theses and Dissertations at Illinois