Biomimetic antimicrobial polymer films and their biomedical and food-packaging applications

Zhang, Yi

Permalink

https://hdl.handle.net/2142/124631 Copy

Description

Title

Biomimetic antimicrobial polymer films and their biomedical and food-packaging applications

Author(s)

Zhang, Yi

Issue Date

2024-03-25

Director of Research (if dissertation) or Advisor (if thesis)

Cao, Qing

Doctoral Committee Chair(s)

Cao, Qing

Committee Member(s)

• Lau, Gee
• Wang, Hua
• Leal, Cecilia

Department of Study

Materials Science & Engineerng

Discipline

Materials Science & Engr

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

Ph.D.

Degree Level

Dissertation

Keyword(s)

• antimicrobial materials
• nanoscale fabrication
• biomedical devices
• food packaging materials

Abstract

In this project, we utilize an innovative approach combining antibacterial nanostructures with high-resolution strain mapping sensor arrays to address orthopedic complications, such as periprosthetic infections and mechanical failures of implants. Initially, our research focuses on employing nanosphere lithography to create antibacterial surfaces. This method allows for precise control over the physical parameters of nanopillar array, facilitating studies that led to a robust understanding of the bactericidal mechanisms involved. Through iterative testing, we enhanced the antibacterial efficacy of these structures. Subsequently, we adopted the anodic aluminum oxide (AAO) template method to scale up nanopillar structure fabrication, demonstrating its potential in food packaging applications. Alongside, we innovated strain sensors for orthopedic implants. By employing transfer printing techniques, we developed ultrathin silicon-based sensors on flexible substrates, creating a comprehensive strain sensing array. This innovation, intended for spine fusion monitoring, also incorporates Bluetooth Low Energy (BLE) technology for wireless, real-time clinical monitoring. In conclusion, this project pioneers significant advancements in both antibacterial structures and strain mapping sensor arrays, offering a new direction for the development of electronic medical applications. These innovations not only address current orthopedic challenges but also lay the groundwork for future technological breakthroughs in medical devices.

Graduation Semester

2024-05

Type of Resource

Thesis

Copyright and License Information

Copyright 2024 Yi Zhang

Owning Collections