Transcranial direct current stimulation in Alzheimer's disease

Sen, Pranay

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https://hdl.handle.net/2142/124454 Copy

Description

Title

Transcranial direct current stimulation in Alzheimer's disease

Author(s)

Sen, Pranay

Issue Date

2024-05-02

Director of Research (if dissertation) or Advisor (if thesis)

Aggarwal, Anu

Department of Study

Electrical & Computer Eng

Discipline

Electrical & Computer Engr

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

M.S.

Degree Level

Thesis

Keyword(s)

• tDCS
• Alzheimer's Disease
• Machine Learning
• Regression

Abstract

The focus of this work was to integrate results from the clinical trials related to transcranial direct current stimulation (tDCS) treatment of Alzheimer’s disease (AD) into a machine learning model of the disease to understand the long term impact of the treatment on disease progression over a decade. The three main contributions of this work are: Firstly, this work proposes the extension of otherwise sparse clinical data for tDCS stimulation AD patients to predict patient outcomes over a decade long period. Secondly, it introduces scientific evidence of long-term improvement in AD with tDCS using brain region volume and MMSE score as key metrics. Thirdly, it calculates an optimal tDCS regimen for improvement in cognitive function for patients with AD. This paper synthesizes data from an emerging field of research (tDCS treatment) into general guidelines for best stimulation practices and potential outcomes which can be replicated to other diseases and treatments.

Graduation Semester

2024-05

Type of Resource

Thesis

Copyright and License Information

Copyright 2024 Pranay Sen

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