URONIC ACIDS IN GAS PHASE

Insausti, Aran

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https://hdl.handle.net/2142/122520 Copy

Description

Title

URONIC ACIDS IN GAS PHASE

Author(s)

Insausti, Aran

Contributor(s)

• Cocinero, Emilio J.
• Çarçabal, Pierre
• Camiruaga, Ander
• Alonso, Elena R.

Issue Date

2023-06-22

Keyword(s)

Conformers and isomers

Abstract

Sugars are versatile molecules that play a variety of roles in the organism. For example, they are important in energy storage processes, cellular recognition or as structural scaffolds. Here, we focus on uronic acids derivatives of the most abundant monosaccharides in the nature, concretely in glucuronic acid (GlcA) and galacturonic acid (GalA). By the combination of high resolution spectroscopy, supersonic expansions and laser ablation as vaporization technique with quantum chemistry calculations we are able to obtain valuable information in gas phase about the bare structures of both anomers of GlcA and GalA (with rotational spectroscopy) and water clusters of the 1-O-phenylated derivative of GlcA (using ion-dip spectroscopy (IR-UV)). Previous studies in the gas phase had been performed on α/β- Glucose1,2 and β-Galactose2,3 where the importance of –CH2OH backbone in H-bond orientation and hydration was reported. In this work, we focus on how the characteristic –COOH group of uronic acids and their anomeric hydroxyl in the H-bond network cooperativity/orientation and microsolvation process.

Publisher

International Symposium on Molecular Spectroscopy

Type of Resource

Text

Language

eng

Handle URL

https://hdl.handle.net/2142/122520

DOI

https://doi.org/10.15278/isms.2023.6995

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