A STORAGE AND SEARCH DEMONSTRATION WITH DNA-ENCODED TEXT

Provencher, Laurel; Bhatia, Swapnil; Mihm, Sean

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https://hdl.handle.net/2142/121123 Copy

Description

Title

A STORAGE AND SEARCH DEMONSTRATION WITH DNA-ENCODED TEXT

Author(s)

• Provencher, Laurel
• Bhatia, Swapnil
• Mihm, Sean

Issue Date

2023

Keyword(s)

• DNA
• sustainability
• storage
• search

Abstract

DNA-based data storage (DDS) holds promise to deliver a paradigm shift for long-term, secure storage of data. To tap into this potential, methods must be developed to produce data-encoding DNA molecules with cost- and time-effective processes. Combinatorial synthesis of DNA molecules from prefabricated fragments of DNA offers a solution to this challenge. We are developing a DNA-based platform combining encoding algorithms, high-throughput synthesis, post-synthesis processing, sequencing, decoding algorithms, and DNA computing architectures into a unified system. DNA datasets encoding images and literary works have been successfully created and translated back into conventional data files containing the entire original set of data or a targeted subset of data. In this work, we demonstrate the ability to search for specific molecules encoding a specific word in a DNA dataset encoding the complete text of multiple literary works.

Series/Report Name or Number

iPRES 2023

Type of Resource

text

Language

en

Copyright and License Information

Copyright held by the author(s). The text of this paper is published under a CC BY-SA license (https://creativecommons.org/licenses/by/4.0/).

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