University of Illinois Urbana-Champaign

The Conformational Panorama Of D-penicillamine: A Laser Ablation Rotational Study.

Herreras, Diego

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https://hdl.handle.net/2142/116887

Description

Title
The Conformational Panorama Of D-penicillamine: A Laser Ablation Rotational Study.
Author(s)
Herreras, Diego
Contributor(s)
  • Alonso, José L.
  • León, Iker
  • Alonso, Elena R.
Issue Date
2022-06-23
Keyword(s)
Structure determination
Abstract
D-Penicillamine, a drug widely used to treat Wilson’s disease, removes copper excess from the human body by acting as a chelating agent. In the present work, we address unveiling this molecule's three-dimensional structure as a first approach to shed light on its mechanism of action. Using a laser ablation source, we have transferred solid D-Penicillamine to the gas phase by laser ablation LA and probed it employing CP-FTWM spectroscopy in the isolated conditions of a supersonic jet. Two dominant conformers of the D-Penicillamine have been identified so far.
Publisher
International Symposium on Molecular Spectroscopy
Type of Resource
text
Language
eng
Handle URL
https://hdl.handle.net/2142/116887&&
DOI
https://doi.org/10.15278/isms.2022.RL09
Copyright and License Information
Copyright 2022 held by the authors

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Abstracts & Presentations - 2022 International Symposium on Molecular Spectroscopy PRIMARY