Rotational Spectrum And Conformational Analysis Of Perillartine: Insights Into The Structure-sweetness Relationship

Juárez, Gabriela

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https://hdl.handle.net/2142/116841 Copy

Description

Title

Rotational Spectrum And Conformational Analysis Of Perillartine: Insights Into The Structure-sweetness Relationship

Author(s)

Juárez, Gabriela

Contributor(s)

• León, Iker
• Alonso, Elena R.
• Alonso, José L.
• Sanz-Novo, Miguel

Issue Date

2022-06-23

Keyword(s)

Structure determination

Abstract

Perillartine, a solid synthetic sweetener, has been brought into the gas phase using laser ablation techniques, and its conformational panorama has been studied using chirped-pulse Fourier transform microwave spectroscopy (LA-CP-FTMW). Four conformers are detected and characterized under the isolation conditions of the supersonic expansion. The four conformers present an E configuration of the C=N group with respect to the double bond of the ring. The observed structures are verified against the Shallenberger-Acree-Kier’s sweetness theory to shed light on the structure-sweetness relationship. The results show that for this particular oxime there is a deluge of possibilities to bind to the receptor.

Publisher

International Symposium on Molecular Spectroscopy

Type of Resource

text

Language

eng

Handle URL

https://hdl.handle.net/2142/116841

DOI

https://doi.org/10.15278/isms.2022.RL04

Copyright and License Information

Copyright 2022 held by the authors

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