Immaculate Conception? Priority and Invention in the CRISPR Patent Dispute
Sherkow, Jacob S.
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https://hdl.handle.net/2142/113711
Description
Title
Immaculate Conception? Priority and Invention in the CRISPR Patent Dispute
Author(s)
Sherkow, Jacob S.
Issue Date
2022-04-20
Keyword(s)
crispr
patent
Zhang
doudna
interference
Abstract
The U.S. Patent Trial and Appeal Board (PTAB), in an interference proceeding decided in February 2022, con- cluded that researchers at the Broad Institute (Cambridge, MA) were the first to ‘‘conceive’’ of using single- guide RNA CRISPR-Cas9 genome editing in eukaryotic cells in 2012. The PTAB reached this verdict even though competing researchers at the University of California, Berkeley, among other institutions, could document the idea 7 months earlier. Understanding the basis for the PTAB’s decision turns on patent law’s particular ‘‘conception’’ requirement. In this study, I explain that requirement, detail the PTAB’s interference decision, and discuss the decision’s practical effects on CRISPR technology and routine science.
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