Development and Application of Three-dimensional Impedance Maps Related to Tissue Pathology
King, Michael R.
Content Files
1_king_michael.pdf
Loading…
Download Files
Loading…
Download Counts (All Files)
Loading…
Edit File
Loading…
Permalink
https://hdl.handle.net/2142/11974
Description
Title
Development and Application of Three-dimensional Impedance Maps Related to Tissue Pathology
Author(s)
King, Michael R.
Issue Date
2009-06-01T16:05:03Z
Director of Research (if dissertation) or Advisor (if thesis)
O'Brien, William D.
Department of Study
Electrical and Computer Engineering
Discipline
Electrical and Computer Engineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
M.S.
Degree Level
Thesis
Date of Ingest
2009-06-01T16:05:03Z
Keyword(s)
Acoustic tissue models
Ultrasonic backscatter
Quantitative ultrasound
Acoustic form factors
Abstract
Three-dimensional acoustic tissue models are a unique means to study ultrasonic scattering by tissue microstructure. In this work, the previous methods used to create and
analyze these models were evaluated and refined. These techniques were then applied to a set of 10 human fibroadenomas, a benign tumor of the breast. These models, called three-dimensional impedance maps (3DZMs), are created from serial sets of histological images which must be properly transformed to recreate the original tissue volume. A
properly reconstructed 3DZM can then be used to estimate properties, such as the effective scatterer size, of the ultrasonic scattering sites in the underlying tissue. These estimates can, in turn, be related to histological features of the tissue. For the
fibroadenoma datasets, the average effective scatterer diameter was estimated to be 84 ± 40 μm when the entire volume was used for analysis. This result compared roughly to the size of the acini in the tissue, although a wide variation was observed in the
histological layout of the tissue.
Use this login method if you
don't
have an
@illinois.edu
email address.
(Oops, I do have one)
IDEALS migrated to a new platform on June 23, 2022. If you created
your account prior to this date, you will have to reset your password
using the forgot-password link below.
1_king_michael.pdf
