Bonds of strength

Phal, Yamuna

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https://hdl.handle.net/2142/109777 Copy

Description

Title

Bonds of strength

Author(s)

Phal, Yamuna

Issue Date

2021

Keyword(s)

• Collagen
• Tissue Engineering

Abstract

Remarkably resistant to mechanical deformations, collagen forms the structural scaffold of connective tissues in humans. One of the most interesting characteristics of collagen fibers is their enormous tensile strength. Combining the advantages of both polarimetry and Infrared (IR) microscopy, IR polarimetric spectroscopic imaging is a unique approach that provides architectural fine structure of bio-molecules such as collagen. A chemical image of pre-cancerous breast tissue is colorized here based on collagen fibrillar content, allowing researchers to study the impact of collagen orientation on the disease progression using only light and computational methods. Designing and implementing microscopes that enable such analytical measurements in IR is the focus of my research. It paves the way for a fast contrast-enhanced imaging platform for collagen scaffolds, which you might even say is the future of tissue engineering.

Type of Resource

Image

Language

eng

Permalink

http://hdl.handle.net/2142/109777

Copyright and License Information

Copyright 2021 Yamuna Phal

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