Preventing bacterial infection of implants for bone regeneration

Dewey, Marley

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https://hdl.handle.net/2142/109746 Copy

Description

Title

Preventing bacterial infection of implants for bone regeneration

Author(s)

Dewey, Marley

Contributor(s)

• Collins, Alan
• Harley, Brendan

Issue Date

2021

Keyword(s)

• Bacterial Infection
• Biomaterials

Abstract

Bacterial infection during surgical operations is a challenge for many tissue engineering approaches for wound healing. One of the design principles of implants to replace missing, damaged, or diseased tissue is preventing the aggregation of bacteria on these. Bacteria present within a wound site can prevent healing and lead to further complications such as abscess formation and additional surgeries to remove the infected tissue. Additionally, some bacterial strains have demonstrated resistance to antibiotics, the typical method to eliminate bacteria. Here, pseudomonas aeruginosa bacteria (orange) adhere to a collagen-based biomaterial (blue) for regeneration of large missing segments of bone. Researchers are currently investigating methods to prevent bacterial adhesion on these biomaterials through the addition of natural manuka honey, which has been shown to disrupt even antibiotic-resistant bacteria.

Type of Resource

Image

Language

eng

Permalink

http://hdl.handle.net/2142/109746

Copyright and License Information

Copyright 2021 Marley Dewey

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