Structures of complexes of cyclooctanone with water

Burevschi, Ecaterina

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https://hdl.handle.net/2142/104324 Copy

Description

Title

Structures of complexes of cyclooctanone with water

Author(s)

Burevschi, Ecaterina

Contributor(s)

• Sanz, M. Eugenia
• Peña, Isabel

Issue Date

2019-06-20

Keyword(s)

Non-covalent interactions

Abstract

\begin{wrapfigure}{r}{0pt} \includegraphics[scale=0.6]{cycloct_abstr.eps} \end{wrapfigure} Water is present in the air with a concentration of up to 4 \%, and also in the olfactory mucosa. Odorants are thus very likely to interact with water before reaching olfactory receptors. We have investigated the complexes of cyclooctanone with water as a first step towards understanding how larger macrocyclic odorants interact with water. Two complexes of the most abundant conformer of cyclooctanone with one water molecule, and two complexes with two water molecules have been characterised using chirped-pulse Fourier Transform Microwave (CP-FTMW) spectroscopy. In the cyclooctanone-H$_{2}$O complexes, water forms a O–H...O hydrogen bond with the carbonyl oxygen of cyclooctanone and two O...H–C hydrogen bonds with the –CH$_{2}$ groups in the cyclooctanone ring. In the cyclooctanone-(H$_{2}$O)$_{2}$ complexes, the second molecule of water binds primarily to the first molecule of water through hydrogen bonding, whilst also forming secondary interactions with the –CH$_{2}$ groups in the ring. The observation of all $^{13}$C isotopic species of the cyclooctanone ring in the complexes in their natural abundances, and of the $^{18}$O species using isotopically enriched water allowed us to calculate the experimental structures of the complexes.

Publisher

International Symposium on Molecular Spectroscopy

Type of Resource

text

Language

eng

Permalink

http://hdl.handle.net/2142/104324

DOI

https://doi.org/10.15278/isms.2019.RH06

Copyright and License Information

Copyright 2019 Ecaterina Burevschi

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