Biosensor and assay development for the detection of disease biomarkers at the point of care
Kwon, Lydia E.
Loading…
Permalink
https://hdl.handle.net/2142/102520
Description
Title
Biosensor and assay development for the detection of disease biomarkers at the point of care
Author(s)
Kwon, Lydia E.
Issue Date
2018-12-13
Director of Research (if dissertation) or Advisor (if thesis)
Cunningham, Brian T.
Department of Study
Bioengineering
Discipline
Bioengineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
M.S.
Degree Level
Thesis
Keyword(s)
biosensor, biomarker, photonic crystal, cancer, disease, diagnostic, screening, point of care, serum, fluorescence, enhanced fluorescence
Abstract
Starting with the advent of biosensors in the late 1950s and early 1960s, biosensors have come to play a major role in various aspects of human life, including our environment, food and drink, safety, and health. In particular, the detection of clinically relevant biomarkers for the screening, diagnosing, and monitoring of diseases such as cancer is an important goal in improving the treatment outcome and the quality of life of patients. In this thesis, an overview of biosensors and their applications is followed by a detailed description of how a photonic crystal biosensor platform with the capacity for fluorescence enhancement was combined with an automated multiplexed microfluidic flow system and an automated spot-finding and data generation algorithm for the detection of a cancer biomarker in human serum and plasma.
Use this login method if you
don't
have an
@illinois.edu
email address.
(Oops, I do have one)
IDEALS migrated to a new platform on June 23, 2022. If you created
your account prior to this date, you will have to reset your password
using the forgot-password link below.
