Glutathione utilization in lactobacillus fermentum CECT 5716

Surya, Agustian

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https://hdl.handle.net/2142/101717 Copy

Description

Title

Glutathione utilization in lactobacillus fermentum CECT 5716

Author(s)

Surya, Agustian

Issue Date

2018-07-17

Director of Research (if dissertation) or Advisor (if thesis)

Miller, Michael J.

Department of Study

Food Science & Human Nutrition

Discipline

Food Science & Human Nutrition

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

M.S.

Degree Level

Thesis

Keyword(s)

Glutathione, Lactobacillus fermentum, Oxidative stress, Metal Stress, Lactic Acid Bacteria

Abstract

Glutathione, a tripeptide antioxidant, has recently been shown to be either utilized or synthesized by gram-positive bacteria, such as Lactic Acid Bacteria. Glutathione plays an important role in countering environmental stress, such as oxidative stress. In this study, cellular activity regarding glutathione in Lactobacillus fermentum CECT 5716 is characterized. We demonstrate that L. fermentum CECT 5716 has a better survival rate in the presence of glutathione under both oxidative and metal stress. As L. fermentum CECT 5716 does not possess the ability to synthesize glutathione, it shows the ability to uptake both reduced and oxidized glutathione from the environment, regenerate reduced glutathione from oxidized glutathione, and perform secretion of glutathione to the environment.

Graduation Semester

2018-08

Type of Resource

text

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http://hdl.handle.net/2142/101717

Copyright and License Information

Copyright 2018 Agustian Surya

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