Retinal mophology and intelligence

Jones, Alicia R.

Permalink

https://hdl.handle.net/2142/101035 Copy

Description

Title

Retinal mophology and intelligence

Author(s)

Jones, Alicia R.

Issue Date

2018-04-20

Director of Research (if dissertation) or Advisor (if thesis)

Khan, Naiman A.

Committee Member(s)

Gothe, Neha P.

Department of Study

Kinesiology & Community Health

Discipline

Kinesiology

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

M.S.

Degree Level

Thesis

Keyword(s)

Retina, IQ, OCT

Abstract

Objective: To investigate the relationship between retinal morphometric measures and intellectual abilities among adults with overweight and obesity. Methods: Adults between 25-45 years (N=55, 38 females) with overweight or obesity (BMI ≥25.0 kg/m2) underwent an optical coherence tomography (OCT) scan to assess retinal nerve fiber layer (RNFL) volume, ganglion cell layer (GCL) volume, total macular volume, and central foveal thickness. Dual-Energy X-ray Absorptiometry was used to assess whole-body adiposity (%Fat). The Kaufman Brief Intelligence Test-2 was used to assess general intelligence (IQ), fluid, and crystallized intelligence. Hierarchical linear regression analyses were performed to examine relationships between adiposity and intelligence measures following adjustment of relevant demographic characteristics and degree of adiposity. Results: Although initial bivariate correlations indicated that %Fat was inversely related to fluid intelligence, this relationship was mitigated by inclusion of other demographic factors, including age, sex, and education level. Regression analyses for primary outcomes revealed that RNFL was positively related to IQ and fluid intelligence. However, only GCL was positively related to crystallized intelligence. Conclusion: This work represents the first study to demonstrate that specific retinal morphometric measures – assessed using OCT – can be utilized to study intellectual abilities among adults with overweight and obesity.

Graduation Semester

2018-05

Type of Resource

text

Permalink

http://hdl.handle.net/2142/101035

Copyright and License Information

Copyright 2018 Alicia Jones

Owning Collections