Brain anatomy: investigations of the effects of aging, fitness, and arterial stiffness

Fletcher, Mark Allen

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Description

Title

Brain anatomy: investigations of the effects of aging, fitness, and arterial stiffness

Author(s)

Fletcher, Mark Allen

Issue Date

2017-05-19

Director of Research (if dissertation) or Advisor (if thesis)

• Fabiani, Monica
• Gratton, Gabriele

Doctoral Committee Chair(s)

• Fabiani, Monica
• Gratton, Gabriele

Committee Member(s)

• Sutton, Brad
• Dye, Matthew

Department of Study

Neuroscience Program

Discipline

Neuroscience

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

Ph.D.

Degree Level

Dissertation

Keyword(s)

• Neuroscience
• Anatomy
• Aging
• Cerebrovascular
• Fletcher
• Fitness

Abstract

This work explores the mechanisms and lifestyle modifiers of brain anatomy throughout the aging process. First, a thorough review of the mechanisms of fitness on brain anatomy is presented. Next, a study examining the effects of aging and fitness on cortical and subcortical brain anatomy in a group of older adults (55-87 years old) is presented. We examine the degree to which cortical, subcortical, and global volumes are sensitive to both age and fitness. Lastly, the effect of cerebrovascular stiffness on the anatomical difference between and within individual subjects is explored across the lifespan (18-75 years old).

Graduation Semester

2017-08

Type of Resource

text

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http://hdl.handle.net/2142/98210

Copyright and License Information

Copyright 2017 Mark Allen Fletcher

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